Greentech Biochemicals Co., Ltd.

DESCRIPTION:                                               

Keratins make up the largest subgroup of intermediate filament (IF) proteins and form a dynamic network of 10–12 nm filaments, built from type I/type II heterodimers, in the cytoplasm of epithelial cells.

FUNCTION：                                                 

1.     A major function of keratin IFs is to protect epithelial cells from mechanical and non-mechanical stresses that cause cell rupture and death. Interference with this role is the root cause of a large number of inherited epithelial fragility conditions.

2. Additional functions, non-mechanical in nature, are manifested in a way that depends on the specific keratin and on the epithelial context. The recent discovery of unusual mutations affecting keratin proteins has uncovered a novel dimension of their mechanical support function, and has synergized with mouse genetics to reveal a role in skin pigmentation. Other studies extended the role of keratin proteins in regulating the response to pro-apoptotic signals, and revealed their ability to modulate protein synthesis and cell size in epithelial cells challenged to grow.

SPECIFICATION                                             

PACKAGING AND SHIPPING                                  

25KG/ Fibre Drum

Drum Size: 40cm*40cm*50cm